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Comparative Gene Finding: Book by Marina Axelson-Fisk

Comparative Gene Finding

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ISBN: 9781447125396    Publisher: Springer London Ltd Year of publishing: 2012     Format:  Paperback No of Pages: 322        
This unique text/reference describes the state of the art in computational gene finding, with a particular focus on comparative approaches. Providing both an overview of the various methods that are applied...Read more
This unique text/reference describes the state of the art in computational gene finding, with a particular focus on comparative approaches. Providing both an overview of the various methods that are applied in the field, and a concise guide on how computational gene finders are built, the book covers a broad range of topics from probability theory, statistics, information theory, optimization theory and numerical analysis. Features: describes how algorithms and sequence alignments can be combined to improve the accuracy of gene finding; introduces the basic biological terms and concepts in genetics, and provides an historical overview of algorithm development; explores the gene features most commonly captured by a computational gene model; discusses the algorithms most commonly used for single-species gene finding; investigates approaches to pairwise and multiple sequence alignments; explains the basics of parameter training; illustrates how to implement a comparative gene finder.
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Review:
From the reviews: "I found it to be a sufficiently comprehensive documentation of gene finding approaches and techniques. ... Therefore, this book's publication was extremely welcome news. Readers...Read more
From the reviews: "I found it to be a sufficiently comprehensive documentation of gene finding approaches and techniques. ... Therefore, this book's publication was extremely welcome news. Readers should really have a good background ... in order to fully benefit from this book. ... synopsis will hopefully give potential readers a fairly good idea of the nature of the book. In summary, this book is as good as it could be for the purposes it states." (M. M. Tanik, ACM Computing Reviews, September, 2010)
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