ISBN: 9781849730914    Publisher: Royal Society Of Chemistry Year of publishing: 2010     Format:  Hard Cover No of Pages: 422        Language: English

Volume 8 solely devoted to the toxicology of metals and metalloids as well as their compounds focuses on human health. Not surprisingly all related research areas are rapidly developing due to the role of metals and metalloids in the environment for the work place for food and water supply etc. Written by 40 internationally recognized experts the 14 stimulating chapters provide an authoritative and timely resource for scientists working in the wide range from analytical physical inorganic and environmental biochemistry all the way through to toxicology physiology and medicine. Volume 8 highlights supported by nearly 1900 references in a comprehensive and timely manner the principles of risk assessment regarding the effects of metals on human health. It examines how metal ions and their compounds affect the pulmonary cardiovascular gastrointestinal (including liver) hematological immune and neurological systems the kidney skin and eyes as well as human reproduction and development. MILS-8 terminates with the role of metal ions as endocrine disrupters in genotoxicity and cancer risk.
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Astrid Sigel has studied languages and was an editor of the Metal Ions in Biological Systems series (until Volume 44) and also of the Handbooks on Toxicity of Inorganic Compounds (1988) on Metals in Clinical and Analytical Chemistry (1994 both with H. G. Seiler) and on Metalloproteins (2001 with Ivano Bertini). Helmut Sigel is Emeritus Professor (2003) of Inorganic Chemistry at the University of Basel Switzerland and a previous editor of the MIBS series until Volume 44. He serves on various editorial and advisory boards published over 300 articles on metal ion complexes of nucleotides coenzymes and other ligands of biological relevance and lectured worldwide. He was named Protagonist in Chemistry (2002) by ICA (issue 339) among further honors are the P. Ray Award (Indian Chemical Society of which he is also an Honorary Fellow) the Werner Award (Swiss Chemical Society) a Doctor of Science honoris causa degree (Kalyani University India) appointments as Visiting Professor (e.g. Austria China Japan UK) and Endowed Lectureships. Roland K. O. Sigel is Associate Professor (2009) of Inorganic Chemistry at the University of Zurich Switzerland from 2003 to 2008 he was endowed with a Forderungsprofessur of the Swiss National Science Foundation. He received his doctoral degree summa cum laude (1999) from the University of Dortmund Germany working with Bernhard Lippert. Thereafter he spent nearly three years at Columbia University New York USA with Anna Marie Pyle (now Yale University). During the six years abroad he received several prestigeous fellowships from various sources and he was awarded the EuroBIC Medal in 2008. His research focuses on the structural and catalytic role of metal ions in ribozymes especially group II introns and on related topics. He was also an editor of Volumes 43 and 44 of the MIBS series.
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